Extraction, characterization and evaluation of Eruca sativa against streptozotocin-induced diabetic nephropathy in rat
نویسندگان
چکیده
منابع مشابه
Ameliorative Effect of Eruca Sativa Extracts on Glucose and Urinary Volume in Streptozotocin-induced Diabetic Rats
Diabetic nephropathy is one of the major complications of diabetes. In recent years, several plant extracts and herbal formulations are used as antidiabetic formulations. It has been suggested that Eruca sativa exert a beneficial antidiabetic effect in rats by reducing oxidative stress. The present research work was designed to evaluate the effect of methanolic and aqueous extracts of Eruca sat...
متن کاملZinc Chloride Protects against Streptozotocin-Induced Diabetic Nephropathy in Rats
Diabetes mellitus (DM) is a health problem affecting millions of individuals worldwide. Diabetic nephropathy (DN), as a significant complication of DM, has become the most common cause of endstage renal failure. Oxidative stress constitutes the key and common events in the pathogenesis of DN and antioxidants may play a beneficial role in its prevention. This study was conducted to investigate t...
متن کاملRenoprotection by Telmisartan versus Benazepril in Streptozotocin Induced Diabetic Nephropathy
Diabetic nephropathy (DN) is one of the major causes of end stage renal disease. Angiotensin converting enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB) are preferred for delaying progression of DN. This study compared the preventive renal effects of telmisartan (10 mg/kg, p.o.), an ARB that completely blocks angiotensin action, and benazepril (5 mg/kg, p.o.), an ACE inhibitor, whi...
متن کاملExtract of Adenanthera pavonina L. seed reduces development of diabetic nephropathy in streptozotocin-induced diabetic rats
Objective: The aim of the present study was to investigate the renal protective effect of Adenanthera pavonina (A. pavonina) seed aqueous extract (APSAE), in streptozotocin (STZ)-induced diabetic rats. Materials and Methods: The renal protective effect of A. pavonina seed aqueous extract (APSAE) was studied in STZ-induced diabetic rats. APSAE (50, 100 and 200 mg/kg per day) was given daily to ...
متن کاملTranscriptomic Analysis in Diabetic Nephropathy of Streptozotocin-Induced Diabetic Rats
Diabetic nephropathy (DN) is a major complication of diabetes and is caused by an imbalance in the expression of certain genes that activate or inhibit vital cellular functions of kidney. Despite several recent advances, the pathogenesis of DN remains far from clear, suggesting the need to carry out studies identifying molecular aspects, such as gene expression, that could play a key role in th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2017
ISSN: 1991-0088
DOI: 10.3329/bjp.v12i2.32065